Prostate Artery Embolization (PAE): 

Find relief from enlarged prostate symptoms and lower urinary tract issues with prostate artery embolization (PAE). This minimally invasive outpatient procedure addresses the source of the problem, offering effective results without surgery or long recovery times.

Understanding PAE

Find relief from enlarged prostate symptoms and lower urinary tract issues with prostate artery embolization (PAE). This minimally invasive outpatient procedure addresses the source of the problem, offering effective results without surgery or long recovery times.

What is prostate artery embolization (PAE)?

Prostate artery embolization (PAE), also referred to as prostatic artery embolization, is a minimally invasive outpatient procedure designed to address benign prostatic hyperplasia (BPH). This non-cancerous condition causes enlargement of the prostate gland, often leading to urinary symptoms.

By blocking the blood supply to specific areas of the enlarged prostate gland, PAE helps shrink the gland and reduces lower urinary tract symptoms, such as frequent urination or weak streams.

What is the main cause of prostate enlargement?

The main cause of prostate enlargement, or BPH, is hormonal changes that occur as men age. These can result in urinary symptoms, including frequent urination, weak streams, or difficulty emptying the bladder—common warning signs of prostate problems.

How does PAE treat benign prostatic hyperplasia (BPH)?

PAE targets the blood flow to the enlarged prostate. Tiny particles are injected to block the arteries carrying the blood supply to the gland. Over a short time frame, this causes the tissue to shrink, relieving bladder pressure and alleviating enlarged prostate symptoms.

Is PAE considered a surgical procedure?

No, prostate artery embolization (PAE) is not considered surgery. It is a minimally invasive procedure where a tiny tube called a catheter is inserted through a small entry point in the arm or leg. An interventional radiologist performs the treatment, using the catheter to reach the blood vessels and treat the prostate without the need for traditional surgery.

Why is PAE called a minimally invasive treatment?

The PAE procedure is minimally invasive because it doesn’t require an incision, sutures, or general anesthesia. Instead, a small puncture in the skin allows for catheter access to the prostate arteries.

Ideal Candidates

Who is the best candidate for PAE?

PAE is ideal for men with BPH who experience moderate to severe lower urinary tract symptoms and want a less invasive alternative to surgery. It’s especially beneficial for those who are not eligible for surgery due to health conditions or the prostate being too large for surgery.

Can men with very large prostates benefit from PAE?

Yes, PAE is effective even for men with very large prostates, a group that may not be suitable for certain surgical treatments.

Is PAE suitable for men who can’t have surgery?

Yes, PAE is a good option for men who have medical conditions that make surgery unsafe or for those who prefer to avoid surgical risks, such as infections, and anesthesia risks, such as heart attacks.

Are there age limits for PAE?

There are no strict age limits, but the patient’s overall health and suitability for the procedure are evaluated on a case-by-case basis.

Can PAE be used for other prostate conditions?

PAE is primarily designed to treat BPH and symptoms of an enlarged prostate. While it is most established for BPH, ongoing research is exploring its potential applications for other prostate conditions, including prostate cancer. However, its role in managing prostate cancer is not yet well-defined and requires further study.
Patients should consult a urologist or interventional radiologist to determine the most appropriate treatment for their specific condition.

Procedure Details

Who is the best candidate for PAE?

PAE is ideal for men with BPH who experience moderate to severe lower urinary tract symptoms and want a less invasive alternative to surgery. It’s especially beneficial for those who are not eligible for surgery due to health conditions or the prostate being too large for surgery.

Can men with very large prostates benefit from PAE?

Yes, PAE is effective even for men with very large prostates, a group that may not be suitable for certain surgical treatments.

Is PAE suitable for men who can’t have surgery?

Yes, PAE is a good option for men who have medical conditions that make surgery unsafe or for those who prefer to avoid surgical risks, such as infections, and anesthesia risks, such as heart attacks.

Are there age limits for PAE?

There are no strict age limits, but the patient’s overall health and suitability for the procedure are evaluated on a case-by-case basis.

Can PAE be used for other prostate conditions?

PAE is primarily designed to treat BPH and symptoms of an enlarged prostate. While it is most established for BPH, ongoing research is exploring its potential applications for other prostate conditions, including prostate cancer. However, its role in managing prostate cancer is not yet well-defined and requires further study.
Patients should consult a urologist or interventional radiologist to determine the most appropriate treatment for their specific condition.

Find out if you are a candidate

Preparation for GAE

How is prostate artery embolization performed?

PAE is performed by inserting a catheter through a small IV-type needle puncture in the groin or wrist. Using x-ray guidance, the interventional radiologist navigates to the prostate arteries and injects embolic particles to block blood flow. This cannot be felt by the patient and is therefore painless.

How long does a PAE procedure take?

The procedure typically takes 1-2 hours, depending on the complexity of the patient’s anatomy.

Do I need general anesthesia for PAE?

No, PAE is usually performed under local anesthesia with sedation, allowing the patient to remain comfortable without the need for full anesthesia. It is what is called “Twilight Medication.”

What technology and imaging are used during PAE?

Advanced imaging techniques, such as fluoroscopy and cone-beam CT, are used to visualize the arteries and guide the catheter during the procedure.

After the Procedure

What can I expect immediately after PAE?

Most patients experience mild discomfort, such as pelvic pain or urinary symptoms, which typically resolve within a few days. You’ll likely stay in the recovery area for observation before being discharged the same day or the next.

When will I notice symptom relief?

Symptom relief can begin within a few weeks, with maximum improvement often seen around 3 months after the procedure.

How soon can I resume daily activities?

Most patients can return to light activities within a few days and full activities within a week, depending on how they feel.

What is the typical recovery time?

Recovery is generally quick, with most discomfort resolving within 1–2 weeks.

Will I need any follow-up care?

Yes, follow-up appointments will be scheduled to monitor your progress and ensure the success of the procedure.

Outcomes and Effectiveness

How effective is PAE for treating BPH?

Prostate artery embolization (PAE) is considered a highly effective treatment for benign prostatic hyperplasia (BPH). Studies report that approximately 80-90% of men experience significant improvement in urinary symptoms following the procedure. These benefits, which include relief from frequent urination, urgency, and weak urine flow, are often sustained for several years.  Additionally, PAE has been shown to reduce prostate volume by 20-40%, contributing to lasting symptom relief.

How long do PAE results last?

The results can last for several years, but some men may require additional treatments if symptoms return.

Can PAE be repeated if symptoms return?

Yes, PAE can be repeated if necessary.

What is the success rate of PAE?

PAE success rate can be understood in two ways:

  • This refers to the ability of the interventional radiologist to complete the procedure as intended. The technical success rate of prostatic artery embolization (PAE) is commonly reported at over 90%. Studies indicate a rate of approximately 95%, demonstrating its reliability as a minimally invasive treatment.

This refers to the percentage of patients who experience significant improvement in their symptoms and quality of life after the procedure. This rate is typically reported to be around 80–90%.

While the procedure is almost always technically successful, a smaller percentage of patients may not achieve the desired level of symptom relief, which is why choosing the right specialist and having thorough follow-up care are so important.

How does prostate size change after PAE?

The prostate typically shrinks by 25–40% over the months following the procedure.

Risks and Medical Considerations

Are there any risks or side effects of PAE?

Prostate artery embolization side effects are usually mild, such as low-grade fever, pelvic discomfort, or temporary urinary symptoms. Rare complications include infection, bleeding, or accidental blockage of nearby blood vessels, though these are uncommon. Overall, PAE is well-tolerated, and complications are rare when performed by experienced doctors.

Can I undergo PAE if I have other health conditions?

Most men with other health issues, including frequent urinary tract infections, can safely undergo PAE. Your doctor will evaluate your risks.

Is PAE covered by insurance?

Coverage varies by insurance provider and location. It’s best to check with your insurance company before the procedure.

Who performs the PAE procedure?

PAE is performed by an interventional radiologist, a specialist trained in minimally invasive procedures.

How does PAE compare to traditional BPH treatments?

PAE offers a minimally invasive option with fewer risks, shorter prostate artery embolization recovery time, and comparable effectiveness for many patients.